Discovery of an orally active non-peptide fibrinogen receptor antagonist

J Med Chem. 1996 May 24;39(11):2118-22. doi: 10.1021/jm960210f.
No abstract available

MeSH terms

  • Adenosine Diphosphate / pharmacology
  • Animals
  • Blood Platelets / drug effects*
  • Carboxylic Acids / chemistry*
  • Carboxylic Acids / pharmacology*
  • Dogs
  • Humans
  • Molecular Structure
  • Oligopeptides / chemistry
  • Oligopeptides / pharmacology
  • Platelet Aggregation / drug effects
  • Platelet Aggregation Inhibitors / chemistry*
  • Platelet Aggregation Inhibitors / pharmacology*
  • Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors*
  • Structure-Activity Relationship

Substances

  • Carboxylic Acids
  • Oligopeptides
  • Platelet Aggregation Inhibitors
  • Platelet Glycoprotein GPIIb-IIIa Complex
  • Adenosine Diphosphate
  • arginyl-glycyl-aspartyl-serine